Spinach Artichoke Chicken Casserole is a cozy, creamy, protein-packed delight that has been a staple in my kitchen. Combining shredded chicken, sautéed spinach, artichokes, and melty cheese, this dish is not only delicious but also fits perfectly into a low-carb, gluten-free diet. The aroma that fills your home while it bakes is simply irresistible, making it a perfect choice for family dinners or meal prep. Let’s dive into this comforting recipe that you’ll want to make again and again!

Why You’ll Love This Spinach Artichoke Chicken Casserole

This dish has several appealing features that make it a favorite:

It’s a one-dish meal, making cleanup a breeze.
Packed with protein from shredded chicken, it’s satisfying and filling.
The creamy texture from cream cheese and sour cream creates a rich mouthfeel.
It’s a great way to sneak in vegetables, making it a healthy option.
Perfect for meal prep, it can be made ahead and reheated.

Low-carb and gluten-free, it aligns with various dietary needs.
Cheesy goodness with mozzarella and Parmesan elevates the flavor.
It’s a comforting dish that’s perfect for any occasion.

Ingredients for Spinach Artichoke Chicken Casserole

Gather these items:

3 cups shredded cooked chicken (rotisserie or leftover)
1 cup marinated artichoke hearts, chopped
2 cups fresh spinach, chopped
4 oz cream cheese, softened

1 cup sour cream
1 cup shredded mozzarella cheese, divided
1/2 cup grated Parmesan cheese
2 cloves garlic, minced
1/2 tsp onion powder
Salt and black pepper, to taste
Olive oil, for sautéing

How to Make Spinach Artichoke Chicken Casserole Step-by-Step

Step 1: Heat oven to 375°F (190°C) and grease a 9×13-inch casserole dish.
Step 2: Warm olive oil in a skillet. Add garlic and cook for 30 seconds. Stir in spinach and cook until wilted, about 2–3 minutes.

Step 3: In a mixing bowl, combine cream cheese, sour cream, onion powder, salt, pepper, and Parmesan. Mix until smooth.
Step 4: Fold in shredded chicken, chopped artichokes, sautéed spinach, and half the mozzarella.
Step 5: Spread the mixture evenly into the casserole dish. Top with remaining mozzarella.
Step 6: Bake for 25–30 minutes until hot, bubbly, and lightly golden.
Step 7: Rest for 5 minutes before serving. Enjoy warm!

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Pro Tips for the Perfect Spinach Artichoke Chicken Casserole

Keep these in mind:

Ensure the cream cheese is fully softened to avoid lumps.

Use fresh spinach for the best flavor and texture.
Feel free to substitute chicken with turkey for a different flavor.
Consider topping with breadcrumbs for an extra crunch.
This dish can also be made in advance and refrigerated before baking.

Best Ways to Serve Spinach Artichoke Chicken Casserole

Here are some serving ideas:

Pair it with a fresh garden salad for a light meal.

Serve it over a bed of quinoa for added texture and nutrition.
Top with additional cheese and bake until bubbly for a cheesy spinach artichoke chicken dish.

How to Store and Reheat Spinach Artichoke Chicken Casserole

To store, cover the casserole tightly with plastic wrap or aluminum foil and refrigerate for up to 3 days. When ready to reheat, simply place it back in the oven at 350°F (175°C) until warmed through, which is perfect for meal prep!

Frequently Asked Questions About Spinach Artichoke Chicken Casserole

What’s the secret to perfect Spinach Artichoke Chicken Casserole?

The secret lies in using well-seasoned shredded chicken and ensuring your cream cheese is softened for a smooth consistency. This will enhance the creamy texture of your casserole.

Can I make Spinach Artichoke Chicken Casserole ahead of time?

Absolutely! You can prepare the casserole up to the baking point and store it in the refrigerator for up to 24 hours. Just bake it when you’re ready to serve.

How do I avoid common mistakes with Spinach Artichoke Chicken Casserole?

To avoid mistakes, make sure to sauté the spinach until fully wilted, and don’t skip resting the casserole after baking, as this allows it to set properly.

Variations of Spinach Artichoke Chicken Casserole You Can Try

Here are some tasty variations:

Use Greek yogurt instead of sour cream for a healthier option.
Incorporate sun-dried tomatoes for an extra burst of flavor.
Make it a low-carb spinach artichoke chicken casserole by serving with cauliflower rice.
Try adding different cheeses like cheddar or gouda for a unique twist.

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For additional information on the health benefits of spinach, you can refer to this Healthline article. It provides insights into why incorporating spinach into your diet is beneficial.